Interviews

Prof. dr. M.H.M. (Marca) Wauben

 

Prof. dr. M.H.M. (Marca) Wauben

Professor Intercellular Communication

Utrecht University, Faculty of Veterinary Medicine

Department of Biomolecular Health Sciences

 

 

Biography:

Marca Wauben is Full Professor in intercellular communication and an expert in deciphering the role of nano-sized cell-derived vesicles (EVs) in intercellular communication in biological systems with emphasis on the immune system. Nowadays, EVs are being recognized as important messengers comprised of selected proteins, (small)RNAs and lipids involved in the modulation of specific target cells. Besides investigating fundamental immunological and regenerative aspects of EV-mediated communication the ‘Wauben EV group’ works on EV-based biomarker discovery, (therapeutic) EV applications and the development of (nano)technology to analyze EVs, e.g. high resolution flow cytometry-based technology enabling single EV-based analysis and sorting. She is author of over n=150 peer reviewed scientific publications and (Co-)recipient of multiple EV-based research grants, e.g. FP7 EU COST Action Microvesicles and Exosomes in Health and Disease (2012; vice-chair), H2020-MSCA-ITN-2016 TRAIN-EV research & training Network (722148) (2017) and H2020-FETOPEN The EV Foundry (801367)(2018). She has been/and is involved in many national and global initiatives to build a scientific community centered around EV-biology; e.g. the founding of the International Society for Extracellular Vesicles (ISEV) in 2011 (currently Secretary General) and scientific journal “Journal of Extracellular Vesicles” (PubMed) (associate editor) and the founding of the Netherlands Society for Extracellular Vesicles (NLSEV) in 2018 (founding President). In 2018 she delivered the Tom Watson oration 2018, University of Sydney, Faculty of Pharmacy (Sydney, Australia) ‘Extracellular vesicles: From biology to biomedical application’ and she received the ISEV Special Achievement award 2019 (at ISEV2019 in Kyoto, Japan).

Edit I Buzás: Be always prepared for the unexpected

 

 Edit I Buzás MD, PhD & DSc

Edit I Buzás is Professor and Chair at Semmelweis University, Department of Genetics, Cell- and Immunobiology, Budapest, Hungary; Head of MTA-SE Immune-Proteogenomics Extracellular Vesicle Research Group, Budapest, Hungary.

Her earlier research at the University of Debrecen (Hungary), Rush University (Chicago, IL, USA) and at McGill University (Montreal, Canada) focused on autoimmunity. She is a laureate of the Carol-Nachman Preis für Rheumatologie (Germany).

Prof Lorraine O’Driscoll: Potential of EVs for benefit in health and disease

 

Prof Lorraine O’Driscoll – Trinity College Dublin, Ireland

Prof Lorraine O’Driscoll is Professor in Pharmacology at the School of Pharmacy and Pharmaceutical Sciences and Trinity Biomedical Sciences Institute, Trinity College Dublin. Following her PhD, Prof O’Driscoll undertook biotechnology/biomedical research for US and EU industry (including Berlex; Archport Ltd-Axonobel; MediSyn Ltd; MedaNova Ltd.) before returning to academic research and teaching.

Bernd Giebel: The current state and the therapeutic potential of MSC derived EVs.

 

PD Dr. rer. nat. Bernd Giebel

Bernd Giebel

Bernd Giebel studied biology at the University zu Köln and received his PhD in 1996 at the Institute for Developmental Biology in Köln. In his thesis he investigated aspects of the Notch signaling pathway during early neurogenesis of Drosophila melanogaster. In 1999 he moved to the Heinrich-Heine-University of Düsseldorf and started to work with human hematopoietic stem and progenitor cells. There, he also established his research group focusing on mechanisms controlling the decision of self-renewal versus differentiation of human somatic stem cells. In 2008 he moved with his group to the Institute of Transfusion Medicine at the University Hospital Essen. Here, he continues his studies on human somatic stem cells. Via the identification of two asymmetrically segregating proteins in dividing human hematopoietic stem and progenitor cells, the tetraspanins CD53 and CD63, he became interested in extracellular vesicles (EVs).